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Anti-BCL2L1 Rabbit Polyclonal Antibody

Leverantör: ProSci Inc.
BCL2L1 encodes a protein which belongs to the BCL-2 protein family. The proteins encoded by BCL2L1 are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis.The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.

BCL2L1 antibody can be used for detection of BCL2L1 by ELISA at 1:312500. BCL2L1 antibody can be used for detection of BCL2L1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Antibody is purified by protein A chromatography method.

Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type:
Antigen: BCL2L1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Dog, Human




 

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Storlek Förp. VWR art.nr Antal
100 µg 100 µG PRSI27-309
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SPECIFIKATIONER

Antigen symbol BCL2L1
Antigen name BCL2-Like 1
Reaktivitet Dog, Human
Conjugation Unconjugated
Clonality Polyclonal
Värd Rabbit
Western blot Yes
ELISA Yes
Antigen synonymer Regulatory Subunit 52, BCLXS, BCL2L, PPP1R52, Apoptosis Regulator Bcl-X, Protein Phosphatase 1
Immunogen A synthetic peptide corresponding a region of human BCL2L1.
Form Lyophilized
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