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Anti-MAP3K8 Rabbit Polyclonal Antibody

Leverantör: ProSci Inc.
MAP3K8 is a member of the serine/threonine protein kinase family. This kinase can activate both the MAP kinase and JNK kinase pathways. This kinase was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This kinase was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. Studies of a similar gene in rat suggested the direct involvement of this kinase in the proteolysis of NF-kappaB1,p105 (NFKB1). This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity.

MAP3K8 antibody can be used for detection of MAP3K8 by ELISA at 1:1562500. MAP3K8 antibody can be used for detection of MAP3K8 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Antibody is purified by protein A chromatography method.

Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type:
Antigen: MAP3K8
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human, Rat, Dog




 

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Storlek Förp. VWR art.nr Antal
100 µg 100 µG PRSI27-310
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SPECIFIKATIONER

Antigen symbol MAP3K8
Antigen name Mitogen-activated Protein Kinase Kinase Kinase 8
Reaktivitet Rat, Human, Dog
Conjugation Unconjugated
Clonality Polyclonal
Värd Rabbit
Western blot Yes
ELISA Yes
Antigen synonymer MEKK8, TPL2, COT, AURA2, EST, Tpl-2, c-COT, ESTF
Immunogen A synthetic peptide corresponding a region of human MAP3K8.
Form Lyophilized
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