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Anti-MAPK3 Rabbit Polyclonal Antibody

Leverantör: ProSci Inc.
ERK1, a MAPK-type protein kinase, is a member of the Ras-MAPK pathway. This pathway modulates the activity of transcription factors, structural proteins, and other protein kinases, leading to biological responses such as cell proliferation and differentiation. Inactive ERK1 associates with MAPK/ERK kinases (MEK) 1 and 2 in the cytosol. Upon stimulation, MEK1/2 phosphorylates and activates ERK1 causing dissociation of the MEK/ERK complex. A portion of the activated ERK1 pool forms dimers and translocates to the nucleus to activate nuclear proteins such as ELK-1 and MSK1. Cytosolic ERK 1 acts on a different set of substrates, including MNK1/2 and MAPKAP-K1.

MAPK3 antibody can be used in immunohistochemistry starting at 1:50, and immunofluorescence.

PBS, 0.1% sodium azide.

PBS, 0.1% sodium azide.

Aliquot and store at -80°C. Avoid multiple freeze-thaw cycles.

Type:
Antigen: MAPK3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Bovine, Dog, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Pig, Rat



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Storlek Förp. VWR art.nr Antal
50 µg 50 µG PRSI48-223
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SPECIFIKATIONER

Antigen symbol MAPK3
Antigen name Mitogen-Activated Protein Kinase 3
Reaktivitet Human, Pig, Bovine, Rat, Dog, Hamster, Mouse, Gorilla, Horse, Monkey
Conjugation Unconjugated
Clonality Polyclonal
Värd Rabbit
Immunokemi Yes
Antigen synonymer PRKM3, ERK1, HS44KDAP, ERK-1, p44-ERK1, ERT2, P44MAPK, p44-MAPK, P44ERK1, HUMKER1A
Immunogen MAPK3 antibody was raised against a peptide located near the internal domain of MAPK3 (Human).
Form Liquid
Tested Applications Immunoaffinity Chromatography
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