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Anti-GPR182 Rabbit Polyclonal Antibody

Leverantör: ProSci Inc.
G Protein-Coupled Receptor L1/G10D (GPR182) has been suggested to be an Adrenomedullin Receptor. Originally cloned from rats and later from humans, L1/G10D does not to bind adrenomedullin or display functional cAMP response to adrenomedullin . The initial experimental results, which demonstrated high-affinity binding and increased levels of cAMP in COS cells that were transfected with L1/G10D and treated with adrenomedullin, could not be reproduced by other laboratories (Kapas et al. 1995). It is now known that the functional adrenomedullin receptor is a heterodimeric complex composed of calcitonin receptor-like receptor (CRLR) and receptor activity modifying proteins (RAMPs) (McLatchie et al. 1998). L1/G10D therefore should be considered an Orphan A receptor.

GPR182 antibody can be used in immunohistochemistry starting at 11 μg/mL.

PBS, 0.1% sodium azide.

PBS, 0.1% sodium azide.

Aliquot and store at -80°C. Avoid multiple freeze-thaw cycles.

Type:
Antigen: GPR182
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Gibbon, Gorilla, Human, Monkey



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Storlek Förp. VWR art.nr Antal
50 µg 50 µG PRSI48-235
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SPECIFIKATIONER

Antigen symbol GPR182
Antigen name G Protein-coupled Receptor 182
Reaktivitet Human, Gibbon, Monkey, Gorilla
Conjugation Unconjugated
Clonality Polyclonal
Värd Rabbit
ELISA Yes
Immunokemi Yes
Antigen synonymer AM-R, ADMR, 7TMR, AMR, gamrh, G10D, hrhAMR
Immunogen GPR182 antibody was raised against a peptide located in the 2nd extracellular domain of GPR182 (Human).
Form Liquid
Tested Applications Immunoaffinity Chromatography
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