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Anti-PDE9A Rabbit Polyclonal Antibody

Leverantör: ProSci Inc.
Phosphodiesterase 9A is a cGMP-specific phosphodiesterase. PDE9A activity is inhibited by zaprinast, but it is insensitive to rolipram, vinpocetine, SKF-94120, dipyridamole, and IBMX. More than 20 alternatively spliced variants have been reported (Rentero et al. 2003). PDE9A has been implicated in penile erectile dysfunction, as well as in functional disturbances in which intraneuronal signal transmission via second messengers are important in the pathophysiology (example, bipolar affective disorder). PDE9A is the only cGMP-specific PDE with significant expression in the forebrain, and as such is likely to function in NO-cGMP signaling.

PDE9A antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.

PBS, 0.1% sodium azide.

PBS, 0.1% sodium azide.

Aliquot and store at -80°C. Avoid multiple freeze-thaw cycles.

Antigen: PDE9A
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Reactivity: Gibbon, Dog, Human, Monkey

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Storlek Förp. VWR art.nr Antal
50 µg 50 µG PRSI48-318
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Antigen symbol PDE9A
Antigen name Phosphodiesterase 9A
Reaktivitet Monkey, Human, Gibbon, Dog
Conjugation Unconjugated
Clonality Polyclonal
Värd Rabbit
Immunokemi Yes
Antigen synonymer HSPDE9A2
Immunogen PDE9A antibody was raised against a peptide located near the internal domain of PDE9A (Human).
Form Liquid
Tested applications Immunoaffinity Chromatography
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